BEMC: Resolving Lord’s Paradox and Why Change-scores Don’t Capture Change (Peter Tennant)
Resolving Lord’s Paradox and Why Change-scores Don’t Capture Change
Peter Tennant, Leeds, UK
Details to follow.
Details to follow.
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The University of Zagreb – School of Medicine, Andrija Štampar School of Public Health and Charité – Universitätsmedizin Berlin, Institute of Public Health in affiliation with the Berlin School of Public Health is organizing a postgraduate continuing medical education course: "How to publish a research paper in a major biomedical journal."
Lecturers:
Tobias Kurth (MD, ScD), Professor, Director of the Institute of Public, Health, Charité - Universitätsmedizin Berlin
Kristina Fišter (MD, MSc, DSc), Assistant Professor, Andrija Štampar School of Public Health, University of Zagreb
Editors of the British Medical Journal (BMJ) and the Canadian Medical Association Journal (CMAJ)
About the Short Course
Publishing visibly is closely linked with success in obtaining grants, yet competition for space is fierce, particularly in major biomedical journals. As research methods evolve and the publishing landscape changes, continuing education in the knowledge and skills needed to produce quality research articles is necessary. This is all the more relevant as capacity is strengthened for health data sciences and decisions are increasingly made based on solid evidence.
Participants will gain knowledge and develop multiple skills needed to produce a high-quality research paper. This includes posing an important and relevant research question, searching biomedical literature, choosing an appropriate study design, writing a research protocol, using electronic data capture solutions, conducting data analysis using the statistical program R and interface RStudio, critically interpreting the findings, and appropriate referencing of previous work. From methods to the manuscript, participants will develop the necessary skills to successfully produce a manuscript suitable for submission to a top biomedical journal.
The course is designed for medical doctors, students, and graduates of biomedical and health disciplines.
Location: Andrija Štampar School of Public Health, Zagreb, Croatia
Language: English
Credits: 3 ECTS points
To Apply
For more information and to apply for the course please email or visit https://mef.unizg.hr/en/how-to-publish-a-research-paper-in-a-major-biomedical-journal
Course Fees
400 €, 300 € for students.
Contact
E-mail: publish(at)mef.hr
Details to follow.
The intent of this intensive short course is to strengthen the methodological skills of the research community. Upon successful completion of the course, participants will have a deeper understanding of methods in causal and prediction research and increased confidence in how to apply these tools in their everyday research practice.
Lecturers:
Rolf H.H. Groenwold, MD, PhD, Leiden University Medical Center (NL)
Maarten van Smeden, PhD, University of Utrecht, Utrecht (NL)
Learning objectives:
By the end of this week, participants should be able to:
Critically assess the results of epidemiological studies on causal relationships or prediction models
Correctly define exposures and learn how to best represent them in models
Understand difference between various sources of bias (confounding, measurement error and missing data) and the way these biases may differentially affect studies on causal relationships and prediction models.
Describe key assumptions of methods used to control for (time-varying) confounding.
Describe key assumptions of methods used to handle missing observations.
Understand the reasons for and consequences of overfitting prediction models
Describe recent developments in the fields of causal research and prediction modelling
Prerequisites:
Basic knowledge of epidemiology
Familiarity with R statistical software (for a short introduction see http://www.r-tutorial.nl/)
Fees:
750 €
510 € for enrolled students (proof required)
3 ECTS
Registration Information:
Tanja Te Gude
Tel. +49 30 450 570 812
The course is for researchers, public health professionals, epidemiologists, and clinicians who want to improve their R coding skills, who want to learn modern tools in the R ecosystem, like the tidyverse and Shiny, or who want to get started writing software in R.
Lecturer: Malcolm Barrett, MPH
Malcolm Barrett is a PhD candidate in epidemiology at the University of Southern California. He studies vision loss and eye diseases that affect vision, like diabetic retinopathy. Specifically, he works on methods to improve the study of how vision impacts quality of life, including tools from psychometrics and causal inference, to make vision-specific quality of life analyses more accurate and more interpretable. In addition to applied research, Malcolm also develops R packages for epidemiologic and biostatistical methods, teaches R, and organizes the Los Angeles R Users Group. He regularly contributes to open source software, including favorite community projects like ggplot2 and R Markdown.
Learning objectives:
At the end of the week, participants will have:
Mastered the tidyverse, a set of principled tools for data science. The tidyverse is a friendly, readable, and fast set of packages intended to work well together, to improve code readability, and to make analyses more reproducible.
Written dynamic documents using best practices for reproducible research, including using R Markdown. R Markdown intertwines code and text so that reports and articles are fully reproducible and exportable to PDF, HTML, Word, and more. R Markdown also has excellent support for citation management and formatting for journals.
Modeled simple statistical and causal problems using both classical regression (linear, logistic) and G-methods.
Written robust functions, programmed with functions, and created a basic R package.
Built ready-to-share web applications entirely in R using the Shiny framework.
Pre-requisites:
Basic epidemiology and statistics. Some experience with R programming will be helpful, but those new to R can take a free introductory course on DataCamp: https://www.datacamp.com/courses/free-introduction-to-r
Materials:
R for Data Science (https://r4ds.had.co.nz/) and Advanced R, ed. 2 (https://adv-r.hadley.nz/), both free online.
Course Information:
Course language: English
ECTS points: 3
Course Fee: 510€ for students, 750€ for other participants
Registration:
Please send an e-mail to Tanja Te Gude
Tel. +49 30 450 570 812
Conference Co-Chairs: Beate Jahn, PhD, Silke Siebert, MD, Tobias Kurth, MD, MSc, ScD, and Uwe Siebert, MD, MPH, MSc, ScD
Call for Abstracts & Short Courses opens December 2019.
Registration opens April 2020.
Details to follow.
Scientific fraud, or better ‘questionable research practices’, are probably as old as science itself. Nowadays, however, there are national and supranational research codes on scientific integrity, academic institutions have installed committees to investigate suspected breaches of scientific integrity, and there is even some research into scientific integrity itself. The lecture will address the relevance of appropriate research attitudes, and the risks of scientific misconduct, and discuss some actual cases, as well as the relation of scientific integrity to its neighboring fields research ethics and research waste.
During this course, participants will in the first part develop a solid foundation of applied principles and methods of epidemiology; use these to evaluate relevant clinical and public health questions; and refine their ability to critically analyze the epidemiologic, clinical, and public health literature. In the second part, participants will learn about paper and proposal writing, writing styles and the editorial process. The format will include lectures, group exercises, and seminars. It is possible to book part 1 and 2 separately.
Lecturers:
Julie E. Buring, ScD, Professor of Medicine, Harvard Medical School and Professor of Epidemiology, Harvard T.H. Chan School of Public Health
Pamela M. Rist, ScD, Assistant Professor of Medicine, Harvard Medical School and Assistant Professor of Epidemiology, Harvard T.H. Chan School of Public Health
Bill Miller, PhD, Professor at Ohio State University, USA
Part 1 23.03.- 24.03. (Julie Buring and Pamela Rist, Harvard University, Boston, MA)
Introductions and Objectives of the Short Course, Critical Thinking in Epidemiology: Examples from the Literature
Types of Epidemiologic Studies in the Literature (Descriptive, Analytic)
Measures of Disease Frequency, Measures of Association and their Scales
Interpretation of the Findings: Association versus Causation
Critical Evaluation of the Medical Literature
Principles of Randomized Trials; Strengths and Weaknesses
Sample size and power, P-values and confidence intervals Screening
Please click here for a detailed schedule.
Part 2, 25.03.-27.03. (Bill Miller, Ohio State University)
Writing styles, manuscript format, paper and proposal writing: overview, writing process, scientific writing exercises, editorial process & reviewing, …
ECTS:
Students can take Parts 1&2 for 3 ECTS, only Part 1 for 1.25 ECTS or only Part 2 for 1.75 ECTS
Fees:
750 € (375 € for one part only)
510 € (255 € for one part only) for enrolled students (proof required)
Venue:
Charité Campus Mitte
Hans-Virchow-Hörsaal
Wilhelm-Waldeyer-Haus
Philippstraße 11
10115 Berlin
Registration:
Please send an e-mail to Tanja Te Gude
Tel. +49 30 450 570 812
Details to follow.
The course introduces students to a general framework for the assessment of comparative effectiveness and safety, with an emphasis of the use of routinely collected data in healthcare settings. The framework relies on the specification and emulation of a hypothetical randomized trial: the target trial. The course explores key challenges for causal inference and critically reviews methods proposed to overcome those challenges. The methods are presented in the context of several case studies for cancer, cardiovascular, and renal diseases.
Course objectives: To learn how to determine “what works” using data from observational and randomized studies.
After successful completion of this course, students will be able to:
Formulate sufficiently well-defined causal questions for comparative effectiveness research
Specify the protocol of the target trial
Design analyses of observational data that emulate the protocol of the target trial
Identify key assumptions for a correct emulation of the target trial
Pre-course reading: Chapters 1-3 of the book Hernán MA, Robins JM (2020). Causal Inference: What If. Boca Raton: Chapman & Hall/CRC, forthcoming. The book can be downloaded (for free) from http://www.hsph.harvard.edu/miguel-hernan/causal-inference-book/
1.25 ECTS
Fees:
312,50 €
212,50 € for enrolled students (proof required)
Registration:
Please send an e-mail to Tanja Te Gude
Tel. +49 30 450 570 812
Causal effects often differ between populations. When causal knowledge is obtained in one setting (for example in the study population of a large randomized controlled trial), extrapolation will usually be necessary in order to justify application of that knowledge in a different setting (for example in a clinically relevant target population). Several different frameworks have been proposed in order to formalize the extrapolation problem. These frameworks have different implications for how researchers should reason about what differences between populations must be accounted for. We propose a new type of causal model in order to formalize the problem, and show how this approach differs from other frameworks including the graphical models proposed by Bareinboim and Pearl. In contrast to these graphical models, our framework can be used to reproduce certain recommendations in the Cochrane Handbook.
Lecturer: Anders Huitfeldt
Location: Zweigbibliothek Campus Charité Mitte – Medizinische Bibliothek der Charité- Just above the CCM medical library. Address: Philippstr. 11, 10115 Berlin.
This course introduces basic and advanced theory underlying propensity score analyses and provides practical insights into the conduct of studies employing the method. Course readings will include propensity score theory as well as applications. Lectures are complemented by computer lab sessions devoted to the mechanics of estimating and using the propensity score as a tool to control for confounding in observational research. Students should have knowledge in multivariable modeling approaches. A course project will involve the application of propensity scores to a data set or the review of a related, published paper.Course Activities: Lectures, readings, homeworks, computer labs, participation, project.
In spite of recent advances in treatment, migraine remains among the top-ranked conditions in the burden of disability globally, especially among women. The prospect of additional migraine treatments is limited by sparse knowledge of fundamental underlying pathophysiologic mechanisms. Recently, genome-wide genetic approaches to migraine in the population are revealing biological functions relevant to migraine, providing insights into its clinical correlates, and addressing the underlying heterogeneity intrinsic to migraine’s clinical presentation
John Gill is Professor of Medicine at the University of British Columbia in Vancouver, Canada. He research interests include clinical research, clinical trials, health policy and health services research related to kidney transplantation. John received the Established Clinical Investigator Award from the American Society of Transplantation in 2017, is Deputy Editor of the American Journal of Transplantation, Officer of the American Society of Transplantation, and is supported by a Foundation Award from The Canadian Institutes of Health Research.
The course is for researchers, public health professionals, epidemiologists, and clinicians who want to improve their R coding skills, who want to learn modern tools in the R ecosystem, like the tidyverse and Shiny, or who want to get started writing software in R.
Date: 02.09. - 06.09.2019
Lecturer: Malcolm Barrett, MPH
Malcolm Barrett is a PhD candidate in epidemiology at the University of Southern California. He studies vision loss and eye diseases that affect vision, like diabetic retinopathy. Specifically, he works on methods to improve the study of how vision impacts quality of life, including tools from psychometrics and causal inference, to make vision-specific quality of life analyses more accurate and more interpretable. In addition to applied research, Malcolm also develops R packages for epidemiologic and biostatistical methods, teaches R, and organizes the Los Angeles R Users Group. He regularly contributes to open source software, including favorite community projects like ggplot2 and R Markdown.
Learning objectives:
At the end of the week, participants will have:
Mastered the tidyverse, a set of principled tools for data science. The tidyverse is a friendly, readable, and fast set of packages intended to work well together, to improve code readability, and to make analyses more reproducible.
Written dynamic documents using best practices for reproducible research, including using R Markdown. R Markdown intertwines code and text so that reports and articles are fully reproducible and exportable to PDF, HTML, Word, and more. R Markdown also has excellent support for citation management and formatting for journals.
Modeled simple statistical and causal problems using both classical regression (linear, logistic) and G-methods.
Written robust functions, programmed with functions, and created a basic R package.
Built ready-to-share web applications entirely in R using the Shiny framework.
Pre-requisits:
Basic epidemiology and statistics. Some experience with R programming will be helpful, but those new to R can take a free introductory course on DataCamp: https://www.datacamp.com/courses/free-introduction-to-r
Materials:
R for Data Science (https://r4ds.had.co.nz/) and Advanced R, ed. 2 (https://adv-r.hadley.nz/), both free online.
Course Information:
Course language: English
ECTS points: 3
Course Fee: 510€ for students, 750€ for other participants
Contact: tanja.tegude@charite.de
Lecturers:
Dr. Dipl.-Vw. Josef Schepers, Berlin Institute of Health
Prof. Dr. Sylvia Thun, Berlin Institute of Health
Prof. Dr. Dr. Felix Balzer and team, Charité - Universitätsmedizin Berlin
Prof. Dr. Igor M. Sauer, Charité - Universitätsmedizin Berlin
Prof. Dr. Bert Arnrich, Hasso-Plattner-Institute
Dr. Kai Heitmann, HL7 Deutschland
Prof. Dr. Markus Feufel, Technical University Berlin
Topics:
Interoperability and standards
Connected Health
Digital Surgery - Extended Reality (XR) and Robotics in Visceral Surgery
Human factors (tbd)
Telemedicine/Remote Patient Monitoring
Data management and registries
Prerequisites:
Basic analytic background (statistics, epidemiology), basic computing skills
Fees:
750 €
510 € for enrolled students (proof required)
Examination: Several multiple choice quizzes
3 ECTS
Contact: tanja.tegude@charite.de
Lecturer:
Matthew Fox, Professor in the Department of Global Health and Epidemiology at Boston University School of Public Health
Learning objectives:
By the end of this week, participants should be able to:
Use the sufficient cause model, counterfactual susceptibility type model, and a causal graph to assist with the design or analysis of an epidemiologic study.
Calculate adjusted measures of effect and select those that, when collapsible, correspond to the no-confounding condition. Use the adjusted measures of effect to estimate the direction and magnitude of confounding.
Distinguish effect measure modification, interdependence, and statistical interaction from one another as separate - but related - concepts of interaction.
Identify the likely magnitude and direction of bias due to misclassification of exposure, outcomes, confounders and modifiers. Weigh the advantages and disadvantages of significance testing.
Compare the advantages and disadvantages of frequentist and Bayesian approaches to analysis of a single study, to eveidence, and to changing your mind.
Prerequisites:
Basic knowledge of epidemiology and biostatistics
Fees:
750 €
510 € for enrolled students (proof required)
3 ECTS
Contact: tanja.tegude@charite.de
Lecturers:
Prof. Dr. Sylvia Thun, Berlin Institute of Health
Prof. Dr. Dr. Felix Balzer, Charité - Universitätsmedizin Berlin
Dipl.-Ing. Andreas Kofler, Charité - Universitätsmedizin Berlin
Prof. Dr. Tim Conrad, Free University Berlin & Zuse Institute Berlin
Dr. Martin Haase, Technical University Berlin
Topics:
Introduction to Health Information Technology
Information Extraction from Electronic Health Records
Terminologies and Ontologies
Introduction to programming
Medical imaging, pattern recognition
Analysis of large data-sets
Data protection and regulatory aspects
Prerequisites:
Basic analytic background (statistics, epidemiology), basic computing skills
Fees:
750 €
510 € for enrolled students (proof required)
Examination: Several multiple choice quizzes
3 ECTS
Panel-discussion: „How is digitalization changing our healthcare system“ with: Peuker (CIO Charité), Stöckemann (CEO Peppermint Venture Partners), Tsimpoulis (Managing Director Doctolib)
The advancement of digitization is the central prerequisite for the successful development of our healthcare system”, according to the website of the German Ministry of Health.
How far did Germany and France get in 2019? How do we as patients, caregivers, scientists and entrepreneurs experience the upheaval and the possibilities that digitalization and new technologies offer?
How do roles and responsibilities for both patients and caregivers change and how do the stakeholders manage this transformation? And is everybody sufficiently aware of the ethical questions which come along when robots and algorithms replace human beings? And after all, will this improve healthcare for the individual?
With this year’s conference, hosted by the Centre Virchow-Villermé for Public Health Paris-Berlin, we invite you to gain an insight into the developments of digitalization in different areas of the healthcare system in Germany and France and to discuss opportunities and implications of digitalization in healthcare on different levels.
Description
This course introduces basic and advanced theory underlying propensity score analyses and provides practical insights into the conduct of studies employing the method. Course readings will include propensity score theory as well as applications. Lectures are complemented by computer lab sessions devoted to the mechanics of estimating and using the propensity score as a tool to control for confounding in observational research. Students should have knowledge in multivariable modeling approaches. A course project will involve the application of propensity scores to a data set or the review of a related, published paper.Course Activities: Lectures, readings, homeworks, computer labs, participation, project. HSPH Course Prerequisite(s): EPI204 or EPI236 or EPI 522 or BST210 or BST213; may not be taken concurrently.
Prerequisite(s)
HSPH Prerequisite: EPI204 or EPI236 or EPI 522 or BST210 or BST213; may not be taken concurrently. Students outside of HSPH must request instructor permission to enroll in this course
With Prof. Jamie Robins, Harvard T.H. Chan School of Public Health. Details will follow.
Lecture with Prof. Maria Glymour.
Further information will follow.
Lecturers: Rolf H.H. Groenwold, MD, PhD, Leiden University Medical Center (NL) &
Maarten van Smeden, PhD, Leiden University Medical Center (NL)
By the end of this week, participants should be able to:
Critically assess the results of epidemiological studies on causal relationships or prediction models
Correctly define exposures and learn how to best represent them in models
Understand difference between various sources of bias (confounding, measurement error and missing data) and the way these biases may differentially affect studies on causal relationships and prediction models.
Describe key assumptions of methods used to control for (time-varying) confounding.
Describe key assumptions of methods used to handle missing observations.
Understand the reasons for and consequences of overfitting prediction models
Describe recent developments in the fields of causal research and prediction modelling
Prerequisites:
Basic knowledge of epidemiology
Familiarity with R statistical software (for a short introduction see http://www.r-tutorial.nl/)
Fees:
750 €
510 € for enrolled students (proof required)
3 ECTS
Registration Information:
Tanja Te Gude
Tel. +49 30 450 570 812
Am 09. Juni 2018 öffneten rund 70 wissenschaftliche Einrichtungen in Berlin und auf dem Potsdamer Telegrafenberg ihre Türen. Mit zahlreichen Experimenten, Vorträgen, Workshops und Mitmachaktionen für Erwachsene und Kinder konnten Besucher*innen Wissenschaft erfahren.
PROGRAMM
17:00
Begrüßung
Prof. Dr. Reinhard Busse Technische Universität Berlin
17:15
Keynote-Lecture
Prof. Dr. Eva Inés Obergfell
Vizepräsidentin für Lehre und Studium der Humboldt-Universität zu Berlin
17:45
Rückblick, Ausblick, Würdigung
Dr. Nina Adelberger
Charité – Universitätsmedizin Berlin
18:00
Laudatio und Verleihung Berlin School of Public Health-Preis
Prof. Dr. Dr. Tobias Kurth
Charité – Universitätsmedizin Berlin
18:30
Get-together